Dr.Phophi Constance Ramathuba (born 15 August 1973) is a South African politician and medical doctor serving as Premier of Limpopo since June 2024. A member of the African National Congress, she was sworn into the provincial legislature in May 2015. Ramathuba served as the Limpopo MEC (Member of the Executive Council) for Health and from May 2015 to June 2024.